مقایسه پارامترهای همودینامیکی پیکربندی‌های پی در پی موازی و ضرب‌دری عروق کرونری در حالت استراحت

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دانشکده مهندسی مکانیک، دانشگاه تربیت مدرس، تهران، ایران

2 دانشکده علوم پزشکی، دانشگاه اراک، اراک، ایران

چکیده

هدف از این پژوهش شبیه سازی جریان خون در پیکربندی‌های با یپس، به منظور پیش بینی بهترین پیکربندی در بیماری با دو گرفتگی 65 و 50 درصد در حالت استراحت است. دامنه محاسباتی از تصاویر CT ساخته شده است. در این تحقیق خون سیالی هموژن، غیرنیوتونی و جریان خون، ضربانی فرض شده است. برای در نظر گرفتن اثرات غیرنیوتونی از مدل کاریو و در خروجی عروق کرونری از مدل لامپ هفت المانی و در خروجی آئورت از مدل سه المانی ویندکسل استفاده شده است. نتایج مقایسه بین پیکربندی‌های پی در پی موازی و ضر بدری نشان می‌دهد، در محل اتصال به صورت موازی با رگ میزبان، در بستر و اطراف ناحیه اتصال کمینه TAWSS کمتر از مقدار بحرانی 4/0 است، همچنین روی رگ پیوندی به سبب انحنای تند شاخه پیوندی، بیشنیه OSI بیشتر از مقدار بحرانی 1/0 است، بنابراین پیوند پی در پی موازی مستعدتر از ضر بدری نسبت به تجمع چربی و بیماری هایی نظیر تورم عروق یا اینتیماهایپرپلاژیا است. از طرفی نتایج پژوهش حاضر نشان می‌دهد با انجام عمل جراحی با یپس پی در پی موازی و ضربدری می‌توان مقادیر بحرانی تنش برشی در ناحیه تنگی را بهبود بخشید و خطر پارگی پلاگ‌های چربی و حرکت توده به سمت عروق پایین دست را کاهش داد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Comparison of the Hemodynamic Parameters of Sequential Parallel and Cross Configurations of Coronary Artery in the Rest State

نویسندگان [English]

  • H. Babakhani 1
  • G. Heidarinejad 1
  • A. Rostami 2
1 Department of Mechanical Engineering, University of Tarbiat Modares, Tehran, Iran
2 University of Arak Medical Sciences, Arak, Iran
چکیده [English]

Numerical simulation of blood flow in Configurations is the aim of this study. In order to predict the best configuration in a patient with double stenosis 65 and 50 percent is examined at rest. The computational domain was created from CT. In this study, blood is assumed homogeneous, non- Newtonian and pulsatile. To consider non-Newtonian effects the Carreau model is used and, a Seven– element lumped model is used in outlet coronary artery and a Three-element Windkessel model is used in outlet aorta. Results of the Comparison between configurations indicate that is TAWSS minimum is less than the critical value 0.4 in the junction in parallel with the host vessel, In bed and the surrounding junction, furthermore OSI maximum is more than critical value 0.1, Because of sharp curvature of graft branch on the vascular graft. The parallel sequential is more prone than cross with respect to fat accumulation and diseases such as intima hyperplasia. The results of this study indicate by doing bypass surgery, sequential parallel and cross can be improve critical values of shear stress in the area of stenosis and it reduced the risk of rupture of plaque fat and moves the heap toward downstream vessels.

کلیدواژه‌ها [English]

  • Blood
  • Non-Newtonian
  • Coronary Artery
  • Configuration
  • Hemodynamic parameter
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