Design, Fabrication and Experimental Study of Spiral Microchannel Particle Separator on Centrifugal Microfluidic Platforms

Document Type : Research Article

Authors

1 Mechanic,mechanic,iran university science and technology,tehran,iran

2 mechanic,Department of Mechanical Engineering, Iran University and Science Technology, Tehran, iran

3 mechanic,Mechanical Engineering,Iran University and Science Technology,Tehran, iran

4 Biomedical Engineering,Iranian Research Organization for Science and Technology, Tehran, iran

Abstract

Nowadays there are a lot of tendencies to use analytical micro-systems in the field of molecular and microbial diagnostics, because of benefits such as less required space, reduced sample and reagent consumption and reduced analysis time. The rotational microfluidic is a sub-branch of the microfluidic systems which by using centrifugal forces, causes the fluid to flow in the networks enclosed in disk-shaped rotating systems. These networks can carry out chemical or biological tests and lead to create more capable devices replaced with current regular devices for medical diagnosis. One of the most commonly used elements in microfluidic systems is the separation element. This element is used to separate particles in the sample by considering mechanical, chemical and electrical specifications. In this study, a novel geometry designed to separate particles passively in microfluidic systems. The spiral microchannel geometry imports the local centrifugal force caused by the curvature of the channel in addition to the centrifugal and the Coriolis forces, to affect the particles and increase the efficiency of the separation. The particle separation process in the proposed channel was studied. The results of the experiments showed high separation efficiency, which indicates the high potential of this element in the separation process.

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References

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Amirkabir Journal of Mechanical Engineering
Volume 53, Issue 3
June 2021
Pages 1359-1372

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